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En roman In Vitro Model af Blast traumatisk hjerneskade
 
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En roman In Vitro Model af Blast traumatisk hjerneskade

Article DOI: 10.3791/58400-v • 08:59 min • December 21st, 2018
December 21st, 2018 •
1,2, 1, 2,3, 1, 4,5, 6, 1,2
1Anaesthetics, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Imperial College London, 2Royal British Legion Centre for Blast Injury Studies, Department of Bioengineering, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Department of Life Sciences, Imperial College London, 5Department of Anaesthetics, Royal Berkshire Hospital NHS Foundation Trust, 6Royal Centre for Defence Medicine, Medical Directorate Joint Force Command

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Dette papir beskriver en ny model af primære blast traumatisk hjerneskade. En komprimeret luft drevet stødrørs stødbølgehastighed bruges til at afsløre i vitro mus hippocampus skive kulturer til en enkelt trykbølge. Dette er en enkel og hurtig protokol skaber en reproducerbare hjernen vævsskade med en høj overførselshastighed.

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Neurovidenskab sag 142 Blast traumatisk hjerneskade primære blast skade blast-induceret neurotrauma stød rør in vitro- model TBI organotypic hippocampus skive kulturer
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