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Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

JoVE 杂志
化学

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JoVE 杂志化学

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

13,708 Views

•

07:33 min

•

October 15, 2018

DOI:

10.3791/57966-v

DOI:

10.3791/57966-v

•

07:33 min

October 15, 2018

•

7 Views

Zainab Ahdash, Andy M. Lau, Chloe Martens, Argyris Politis

¹Department of Chemistry,King’s College London

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Protein Architecture Protein-ligand Complex Structural Mass Spectrometry Native Mass Spectrometry Biomolecular Assemblies Heterogeneous Protein Samples Oligomeric State Nanoelectrospray Ammonium Acetate Ion Mobility Separation Capillary Holder Nano-flow Gas Pressure Capillary Voltage Sampling Cone Source Offset Source Temperature Cone Gas Flow Trap Collision Energy Trap Voltage

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