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Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating

Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating

7,045 Views

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05:35 min

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June 23, 2018

DOI:

10.3791/56879-v

DOI:
10.3791/56879-v

•

05:35 min
June 23, 2018

•

1 Views
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1Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering,Chinese Academy of Medical Science & Peking Union Medical College

Summary

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This protocol aims to achieve surface engineering of pancreatic islets using a heparin-incorporated starPEG nanocoating via pseudo-bioorthogonal chemistry between the N-hydroxysuccinimide groups of the nanocoating and the amine groups of islet cell membrane.

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Cite this Article

Yang, J., Lou, S., Kong, D., Li, C. Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating. J. Vis. Exp. (136), e56879, doi:10.3791/56879 (2018).

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