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Automated acoustique de distribution pour la Dilution série de Peptide Agonistes dans Potency Détermination Assays
JoVE 杂志
生物化学
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JoVE 杂志 生物化学
Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

Automated acoustique de distribution pour la Dilution série de Peptide Agonistes dans Potency Détermination Assays

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08:06 min

November 10, 2016

DOI:

08:06 min
November 10, 2016

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Summary

Automatically generated

Peptide adsorption to plasticware during traditional tip-based serial dilutions can significantly impact potency determination and confound the understanding of structure-activity relationships used for lead identification and lead optimization phases of drug discovery. Here methods for automated acoustic non-contact serial dilution of peptide samples are described.

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