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Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans
JoVE 杂志
发育生物学
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JoVE 杂志 发育生物学
Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans

Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans

7,898 Views

10:55 min

February 22, 2015

DOI:

10:55 min
February 22, 2015

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Summary

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We describe the detailed steps of a high-throughput chemical assay in the nematode Caenorhabditis elegans used to assess germline toxicity. In this assay, disruption of germline function following chemical exposure is monitored using a fluorescent reporter specific to aneuploid embryos.

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