Journal
/
免疫与感染
/
Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products
JoVE 杂志
免疫与感染
This content is Free Access.
JoVE 杂志 免疫与感染
Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

17,696 Views

•

12:40 min

•

April 06, 2015

DOI:

10.3791/52412-v

DOI:
10.3791/52412-v

•

12:40 min
April 06, 2015

•

9 Views
, , , , , , ,
1Institute of Immunology and Infection Research,University of Edinburgh, 2Manchester Collaborative Centre for Inflammation Research

Summary

Automatically generated

Heligmosomoides polygyrus is a murine nematode with powerful immunomodulatory capabilities that closely resemble those of highly-prevalent human helminth infection. Here we describe a protocol for the long-term maintenance of the H. polygyrus lifecycle.

Explore More Videos

Heligmosomoides PolygyrusNematospiroides DubiusH. BakeriGastrointestinal HelminthImmunomodulatoryChronic InfectionMiceHelminth-derived Immune RegulationAllergyAutoimmunityL3 LarvaeAdult ParasitesExcretory-secretory ProductsHES

Read Article

Cite this Article

Johnston, C. J. C., Robertson, E., Harcus, Y., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J., Maizels, R. Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products. J. Vis. Exp. (98), e52412, doi:10.3791/52412 (2015).

Download .ris file

Copy

Share Video

.

Copy