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Lineage-omprogrammering av Pericyte-härledda celler i den vuxna mänskliga hjärnan i inducerade Nervceller

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神经科学

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JoVE 杂志神经科学

Lineage-reprogramming of Pericyte-derived Cells of the Adult Human Brain into Induced Neurons

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Lineage-omprogrammering av Pericyte-härledda celler i den vuxna mänskliga hjärnan i inducerade Nervceller

12,147 Views

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09:36 min

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May 12, 2014

DOI:

10.3791/51433-v

DOI:

10.3791/51433-v

•

09:36 min

May 12, 2014

•

1 Views

Marisa Karow, Christian Schichor, Ruth Beckervordersandforth, Benedikt Berninger⁴

¹Department of Physiological Genomics, Institute of Physiology,Ludwig Maximilians University Munich, ²Tumor Biology Lab, Neurosurgical Clinic,Ludwig-Maximilians University Munich, ³Institut für Biochemie, Emil-Fischer-Zentrum,Friedrich-Alexander-Universität Erlangen-Nürnberg, ⁴Institute of Physiological Chemistry and Focus Program Translational Neuroscience,Johannes Gutenberg University Mainz

Tags

Lineage-reprogramming Pericyte Adult Human Brain Induced Neurons Direct Conversion Neurogenesis In Vitro Modeling Brain Repair Cerebral Cortex PDGF Receptor-β CD146 Sox2 Ascl1 Pericyte-derived Induced Neurons Patch-clamp Recording

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