Journal
/
神经科学
/
Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
JoVE 杂志
神经科学
需要订阅 JoVE 才能查看此.  登录或开始免费试用。
JoVE 杂志 神经科学
Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

11,357 Views

•

07:35 min

•

February 04, 2014

DOI:

10.3791/50864-v

DOI:
10.3791/50864-v

•

07:35 min
February 04, 2014

•

6 Views
,
1Department of Psychiatry,Harvard Medical School, 2Mailman Research Center,McLean Hospital

Summary

Automatically generated

Approaches for testing the effects of antipsychotic drugs (APDs) in Caenorhabditis elegans are demonstrated. Assays are described for testing drug effects on development and viability and on pharyngeal pumping rate. These methods are also applicable for pharmacogenetic experiments with drug classes other than APDs.

Explore More Videos

Caenorhabditis ElegansAntipsychotic DrugsPharmacogenetic StudiesDevelopmental AssayPharyngeal PumpingNeurotransmitter SynthesisSynaptic Structure And FunctionForward And Reverse Genetic ScreensChemical Genetic Screens

Read Article

Cite this Article

Hao, L., Buttner, E. A. Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans. J. Vis. Exp. (84), e50864, doi:10.3791/50864 (2014).

Download .ris file

Copy

Share Video

.

Copy