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A Caenorhabditis elegans Model System for Amylopathy Study
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May 17, 2013
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We describe methods to study aspects of amylopathies in the worm C. elegans. We show how to construct worms expressing human Aβ42 in neurons and how to test their function in behavioral assays. We further show how to obtain primary neuronal cultures that can be used for pharmacological testing.
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Duan, Z., Sesti, F. A Caenorhabditis elegans Model System for Amylopathy Study. J. Vis. Exp. (75), e50435, doi:10.3791/50435 (2013).
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