需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
25,416 Views
•
09:54 min
•
August 10, 2012
DOI:
Summary
Automatically generated
Dopamine is distinctly regulated in the midbrain nuclei, which contain the cell bodies and dendrites of the dopamine neurons. Here we describe a dissection and sample-handling approach to maximize results, and thus conclusions and insights, on dopamine regulation in the midbrain nuclei of the substantia nigra (SN) and ventral tegmental area (VTA) in rodents.
Explore More Videos
Dopamine RegulationNeurotransmitterCNSLocomotor ActivityReward-related BehaviorMolecular DeficienciesNigrostriatal PathwayMesoaccumbens PathwayStriatumNucleus AccumbensTyrosine Hydroxylase ProteinTH PhosphorylationDopamine Transporter ProteinVesicular Monoamine Transporter 2 ProteinPost-translational ModificationsMidbrain
Read Article
Cite this Article
Salvatore, M. F., Pruett, B. S., Dempsey, C., Fields, V. Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area. J. Vis. Exp. (66), e4171, doi:10.3791/4171 (2012).
Copy