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Journal / Bioengineering / Silk Film Culture System for in vitro Analysis…
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Bioengineering

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JoVE Journal Bioengineering
Silk Film Culture System for in vitro Analysis and Biomaterial Design
 

Silk Film Culture System for in vitro Analysis and Biomaterial Design

Article DOI: 10.3791/3646-v • 11:19 min • April 24th, 2012
April 24th, 2012 •
1, 1, 1, 2, 1
1Margaret M. Dyson Vision Research Institute, Weill Cornell Medical College, 2Department of Biomedical Engineering, Tufts University

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Silk films are a novel class of biomaterials readily customizable for an array of biomedical applications. The presented silk film culture system is highly adaptable to a variety of in vitro analyses. This system represents a biomaterial design platform offering in vitro optimization before direct translation to in vivo models.

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Silk Film Culture System In Vitro Analysis Biomaterial Design Protein-based Biomaterials High Fidelity Fabrication Research Laboratory Environment Controllable Dimensional And Material Characteristics Biocompatible Cell Adhesion Topographic Patterning Surface Modification Depot For Biologically Active Molecules Drug Delivery Applications Custom Design Dissolution And Degradation Properties Transparency For Imaging Applications Cell-silk Film Surface Interactions Cell Proliferation Alignment Time-lapse Phase-contrast Imaging Scanning Electron Microscopy Metabolic Activity Nucleic Acid Content
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