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An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
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An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

17,991 Views

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10:35 min

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November 28, 2010

DOI:

10.3791/2146-v

DOI:
10.3791/2146-v

•

10:35 min
November 28, 2010

•

7 Views
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1Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Womans Health, Department of Obstetrics and Gynecology,University of Pennsylvania-School of Medicine, 2Women’s Cancer Program,Fox Chase Cancer Center

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Orthotopic ModelSerous Ovarian CancerImmunocompetent MiceIn Vivo Tumor ImagingTumor Immune ResponsesTg-MISIIR-TAg Transgenic Mouse ModelSV40 Transforming RegionMullerian Inhibitory Substance Type II Receptor (MISIIR) Gene PromoterSyngeneic Allograft RecipientsPreclinical StudiesTumor Microenvironment

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Nunez-Cruz, S., Connolly, D. C., Scholler, N. An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses. J. Vis. Exp. (45), e2146, doi:10.3791/2146 (2010).

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