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Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits
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January 21, 2010
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Controlling and analyzing neural circuits in vivo would be facilitated by a technology for delivery of viruses and other reagents to desired 3-dimensional sets of brain regions. We demonstrate customized fluidic injector array fabrication, and delivery of virally-encoded optical sensitizers, enabling optical manipulation of complex brain circuits.
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Chan, S., Bernstein, J., Boyden, E. Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits. J. Vis. Exp. (35), e1489, doi:10.3791/1489 (2010).
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