1Center for Bionics and Pain Research, 2Center for Advanced Reconstruction of Extremities,Sahlgrenska University Hospital, 3Department of Electrical Engineering,Chalmers University of Technology, 4Bionics Institute, 5IV Clinica Ortoplastica,IRCCS Istituto Ortopedico Rizzoli, 6Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy,University of Gothenburg, Sahlgrenska University Hospital, 7Department of Orthopedic Surgery, Hand Unit,Worker Hospital, 8College of Medicine and Veterinary Medicine, The Queen’s Medical Research Institute,The University of Edinburgh, 9Canniesburn Plastic Surgery Unit,Glasgow Royal Infirmary, 10College of Medicine, Veterinary & Life Sciences,The University of Glasgow, 11Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry,University of Alberta, 12Plastics and Reconstructive Surgery, Dandenong Hospital,Monash Health, 13Division of Plastic and Reconstructive Surgery,Massachusetts General Hospital & Harvard Medical School, 14Division of Plastic Surgery, Department of Surgery,Northwestern Feinberg School of Medicine, 15Section of Plastic Surgery, Department of Surgery,Michigan Medicine, 16Medical Bionics Department,University of Melbourne, 17Prometei Pain Rehabilitation Center
ここでは、切断後の神経障害性疼痛を治療するための再生末梢神経インターフェース(RPNI)手術を行う外科的処置について、国際的なランダム化比較試験(RCT)の文脈で説明します(ClinicalTrials.gov、NCT05009394)。このRCTでは、RPNIを他の2つの外科的技術、すなわち標的筋再神経支配(TMR)および神経腫切除と筋肉内転位と組み合わせたものと比較しています。
