1Center for Bionics and Pain Research, 2Center for Advanced Reconstruction of Extremities,Sahlgrenska University Hospital, 3Department of Electrical Engineering,Chalmers University of Technology, 4Bionics Institute, 5IV Clinica Ortoplastica,IRCCS Istituto Ortopedico Rizzoli, 6Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy,University of Gothenburg, Sahlgrenska University Hospital, 7Department of Orthopedic Surgery, Hand Unit,Worker Hospital, 8College of Medicine and Veterinary Medicine, The Queen’s Medical Research Institute,The University of Edinburgh, 9Canniesburn Plastic Surgery Unit,Glasgow Royal Infirmary, 10College of Medicine, Veterinary & Life Sciences,The University of Glasgow, 11Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry,University of Alberta, 12Plastics and Reconstructive Surgery, Dandenong Hospital,Monash Health, 13Division of Plastic and Reconstructive Surgery,Massachusetts General Hospital & Harvard Medical School, 14Division of Plastic Surgery, Department of Surgery,Northwestern Feinberg School of Medicine, 15Section of Plastic Surgery, Department of Surgery,Michigan Medicine, 16Medical Bionics Department,University of Melbourne, 17Prometei Pain Rehabilitation Center
Qui, descriviamo la procedura chirurgica per eseguire la chirurgia rigenerativa dell’interfaccia nervosa periferica (RPNI) per il trattamento del dolore neuropatico post-amputazione nel contesto di uno studio internazionale randomizzato controllato (RCT) (ClinicalTrials.gov, NCT05009394). L’RCT confronta l’RPNI con altre due tecniche chirurgiche, vale a dire la reinnervazione muscolare mirata (TMR) e l’escissione del neuroma combinata con la trasposizione intramuscolare.
