Murine Model for Studying Leptomeningeal Disease Using Circulating Tumor Cells
1Department of Tumor Biology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Neuro-Oncology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Cancer Physiology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 4Department of Comparative Medicine,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute
En este artículo se describe un protocolo para la propagación de células tumorales circulantes por líquido cefalorraquídeo (CTC-LCR) recolectadas de pacientes con enfermedad leptomeníngea asociada a melanoma (M-LMD) para desarrollar modelos preclínicos para estudiar la M-LMD.
