Murine Model for Studying Leptomeningeal Disease Using Circulating Tumor Cells
1Department of Tumor Biology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Neuro-Oncology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Cancer Physiology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 4Department of Comparative Medicine,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute
Este artigo descreve um protocolo para a propagação de células tumorais circulantes do líquido cefalorraquidiano (LCR-CTCs) coletadas de pacientes com doença leptomeníngea associada ao melanoma (M-LMD) para desenvolver modelos pré-clínicos para estudar M-LMD.
