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Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
February 02, 2024
一种基于流式细胞术的高通量技术筛选整合素抑制药物
00:45 min
•
使用从人血液中分离的中性粒细胞以 384 孔板形式对化合物进行高通量筛选
02:35 min
•
使用流式细胞术的中性粒细胞筛选测定
01:03 min
•
Ziming Cao
,
Matthew J. Garcia
,
Larry A. Sklar
3,4,5
,
Angela Wandinger-Ness
4
,
Zhichao Fan
1
Department of Immunology, School of Medicine
,
UConn Health
,
2
Center for Molecular Discovery
,
University of New Mexico Health Sciences Center
,
3
Comprehensive Cancer Center
,
University of New Mexico Health Sciences Center
,
4
Department of Pathology
,
University of New Mexico Health Sciences Center
,
5
Autophagy, Inflammation, & Metabolism (AIM) Center
,
University of New Mexico
Summary
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该协议描述了一种基于流式细胞术的高通量筛选方法,用于鉴定抑制人中性粒细胞上β2整合素活化的小分子药物。
Article