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A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor
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JoVE Journal Chemistry
A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor

A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor

English

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2,543 Views

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05:21 min

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February 10, 2023

DOI:

10.3791/64937-v

DOI:
10.3791/64937-v

•

05:21 min
February 10, 2023

•

18 Views
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1Shenzhen Hwagen Pharmaceutical Co., Ltd, 2Guangdong Raffles Pharmaceutical Technology Co., Ltd

Summary

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A detailed scalable continuous flow protocol is presented to synthesize an aryl fluoride from an aryl amine through the Balz-Schiemann reaction.

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Cite this Article

Zhou, Z., Wang, Y., Liu, S., Phillis, A., Zhang, Q., Ye, W. A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor. J. Vis. Exp. (192), e64937, doi:10.3791/64937 (2023).

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