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Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents
JoVE Journal
Behavior
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JoVE Journal Behavior
Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents

Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents

DOI:
10.3791/64754-v

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04:41 min

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December 02, 2022

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, , , ,
1Laboratory of Cognitive and Behavioral Neuroscience, Graduate School of Brain Science,Doshisha University

Chapters

  • 00:04Introduction
  • 01:06Evaluation of Spacial Navigation of Rodents in the Reconfigurable Maze
  • 01:47Behavioral Experiment, Performance, and Data Analysis
  • 02:48Results: Maze Shapes in a Single Environment, Maze Expansion and Trajectories of a Rat, and the Performance of Maze Experiments
  • 04:08Conclusion

Summary

Automatic Translation

Automatic Translation

The present protocol describes a reconfigurable maze, a unique system for testing spatial navigation and behavioral phenotypes in rodents. The adaptability of this maze system enables the execution of various experiments in a single physical environment. The ease of structural rearrangement generates reliable and reproducible experimental results.

Tags

Keywords: Reconfigurable MazeSpatial NavigationRodentsBehavioral TestingMaze ConfigurationDelayed Alternation TaskTreadmillPose EstimationReproducibility

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