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03:56 min
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December 16, 2022
DOI:
1Division of Anesthesiology and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 2Department of Anesthesiology and Perioperative Medicine,Mayo Clinic, 3Department of Biochemistry and Physiology of the Faculty of Biology and Ecology,Oles Gonchar of the Dnipro National University, 4Department of Ophthalmology, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev
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The present protocol describes a rat model of fluid percussion-induced traumatic brain injury followed by a series of behavioral tests to understand the development of dominant and submissive behavior. Using this model of traumatic brain injury in conjunction with specific behavioral tests enables the study of social impairments following brain injury.
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Frank, D., Gruenbaum, B. F., Semyonov, M., Binyamin, Y., Severynovska, O., Gal, R., Frenkel, A., Knazer, B., Boyko, M., Zlotnik, A. Assessing Dominant-Submissive Behavior in Adult Rats Following Traumatic Brain Injury. J. Vis. Exp. (190), e64548, doi:10.3791/64548 (2022).
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