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Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain

2,609 Views

09:44 min

May 20, 2022

DOI:

09:44 min
May 20, 2022

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Summary

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The ability to permanently mark stem cells and their progeny with a fluorophore using an inducible transgenic lineage tracing mouse line allows for spatial and temporal analysis of activation, proliferation, migration, and/or differentiation in vivo. Lineage tracing can reveal novel information about lineage commitment, response to intervention(s), and multipotency.

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