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Fabrication of Micro-Patterned Chip with Controlled Thickness for High-Throughput Cryogenic Electron Microscopy
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April 21, 2022
DOI:
1Department of Biomedical-Chemical Engineering,The Catholic University of Korea, 2Department of Biotechnology,The Catholic University of Korea, 3School of Chemical and Biological Engineering, and Institute of Chemical Processes,Seoul National University, 4Center for Nanoparticle Research,Institute of Basic Science (IBS), 5Institute of Engineering Research, College of Engineering,Seoul National University, 6Advanced Institutes of Convergence Technology,Seoul National University
Summary
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A newly developed micro-patterned chip with graphene oxide windows is fabricated by applying microelectromechanical system techniques, enabling efficient and high-throughput cryogenic electron microscopy imaging of various biomolecules and nanomaterials.
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Kang, M., Lee, M., Kang, S., Park, J. Fabrication of Micro-Patterned Chip with Controlled Thickness for High-Throughput Cryogenic Electron Microscopy. J. Vis. Exp. (182), e63739, doi:10.3791/63739 (2022).
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