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结合3D打印和静电纺丝来制造仿生心脏瓣膜传单

JoVE Journal
Medicine

This content is Free Access.

JoVE Journal Medicine

Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets

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结合3D打印和静电纺丝来制造仿生心脏瓣膜传单

3,718 Views

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10:29 min

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March 23, 2022

DOI:

10.3791/63604-v

DOI:

10.3791/63604-v

•

10:29 min

March 23, 2022

•

23 Views

Benedikt Freystetter¹, Maximilian Grab^1,2, Linda Grefen¹, Lara Bischof¹, Lorenz Isert³, Petra Mela², Deon Bezuidenhout⁴, Christian Hagl^1,5, Nikolaus Thierfelder¹

¹Department of Cardiac Surgery,Ludwig Maximilians University Munich, ²Chair of Medical Materials and Implants,Technical University Munich, ³Faculty for Chemistry and Pharmacy,Ludwig Maximilians University Munich, ⁴Cardiovascular Research Unit,University of Cape Town, ⁵DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance

Summary

所提出的方法为三维（3D）支架（例如心脏瓣膜传单）中的仿生纤维结构工程提供了一种创新方法。3D打印的导电几何形状用于确定形状和尺寸。纤维取向和特性可针对每层单独调整。可以在一次设置中制造多个样品。

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