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Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets
JoVE Journal
Medicina
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JoVE Journal Medicina
Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets

Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets

DOI:
10.3791/63604-v

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10:29 min

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March 23, 2022

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, , , , , , , ,
1Department of Cardiac Surgery,Ludwig Maximilians University Munich, 2Chair of Medical Materials and Implants,Technical University Munich, 3Faculty for Chemistry and Pharmacy,Ludwig Maximilians University Munich, 4Cardiovascular Research Unit,University of Cape Town, 5DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance

Capítulos

  • 00:04Introduction
  • 00:35Preparation of 3D Printing Model and Spinning Solution
  • 02:45Electrospinning Setup
  • 04:05Electrospinning Process
  • 07:01Postprocessing and Sample Acquisition
  • 07:34Results: 3D-Printed Biomimetic Heart Valve Leaflets
  • 09:47Conclusion

Summary

Tadução automática

Tadução automática

The presented method offers an innovative way for engineering biomimetic fiber structures in three-dimensional (3D) scaffolds (e.g., heart valve leaflets). 3D-printed, conductive geometries were used to determine shape and dimensions. Fiber orientation and characteristics were individually adjustable for each layer. Multiple samples could be manufactured in one setup.

Tags

3D PrintingElectrospinningBiomimeticHeart Valve LeafletsTriple-layered StructuresOriented FibersSTL FileSlicing SoftwarePrinting ParametersSpinning SolutionPolyurethaneCollectorElectrospinning SetupCathodeAnode

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