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一种由工程成纤维细胞生长因子1刺激的Descemet剥离的人类角膜器官培养模型，仅具有加速愈合
JoVE Journal
Medicine
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JoVE Journal Medicine
A Human Corneal Organ Culture Model of Descemet’s Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
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一种由工程成纤维细胞生长因子1刺激的Descemet剥离的人类角膜器官培养模型，仅具有加速愈合

English

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4,254 Views

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12:36 min

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July 22, 2022

DOI:

10.3791/63482-v

DOI:
10.3791/63482-v

•

12:36 min
July 22, 2022

•

3 Views
, , ,
1Trefoil Therapeutics, Inc.

Summary

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Descemet的剥离只是一种实验程序，其中由Fuchs内皮角膜营养不良引起的中央角膜内膜的患者剥离Descemet的膜，以便外周细胞再生内皮层。我们提出了在营养不良性人角膜 离体 模拟DSO的新方法，其eFGF1（NM141）刺激加速愈合。

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Pizzuto, S., Duffey, G., Weant, J., Eveleth, D. A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1. J. Vis. Exp. (185), e63482, doi:10.3791/63482 (2022).

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