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扩展轴突转运体内成像工具包

JoVE Journal
Neuroscience

This content is Free Access.

JoVE Journal Neuroscience

Expanding the Toolkit for In Vivo Imaging of Axonal Transport

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扩展轴突转运体内成像工具包

2,901 Views

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09:24 min

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December 23, 2021

DOI:

10.3791/63471-v

DOI:

10.3791/63471-v

•

09:24 min

December 23, 2021

•

8 Views

Andrew P. Tosolini^1,2, David Villarroel-Campos^1,2,3, Giampietro Schiavo^1,2,3, James N. Sleigh^1,2,3

¹Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology,University College London, ²UCL Queen Square Motor Neuron Disease Centre,University College London, ³UK Dementia Research Institute,University College London

Summary

使用转基因荧光小鼠，描述了详细的方案，以评估活体动物完整坐骨神经的运动和感觉轴突内信号内体和线粒体的体内轴突转运。

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