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Messung der Glukoseaufnahme in Drosophila-Modellen der TDP-43-Proteinopathie
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Neuroscience
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JoVE Journal Neuroscience
Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy
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Messung der Glukoseaufnahme in Drosophila-Modellen der TDP-43-Proteinopathie

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2,599 Views

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07:07 min

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August 03, 2021

DOI:

10.3791/62936-v

DOI:
10.3791/62936-v

•

07:07 min
August 03, 2021

•

20 Views
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1Department of Molecular and Cellular Biology,University of Arizona, Tucson, 2Vollum Institute,Oregon Health and Science University, 3Department of Neuroscience,University of Arizona, Tucson

Summary

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Die Glukoseaufnahme ist in Drosophila-Motoneuronen erhöht, die von der TAR-DNA-bindenden Protein (TDP-43) -Proteinopathie betroffen sind, wie durch einen FRET-basierten, genetisch kodierten Glukosesensor angezeigt.

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Cite this Article

Loganathan, S., Ball, H. E., Manzo, E., Zarnescu, D. C. Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy. J. Vis. Exp. (174), e62936, doi:10.3791/62936 (2021).

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