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Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
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Chemistry
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JoVE Journal Chemistry
Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

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3,042 Views

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05:45 min

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June 08, 2021

DOI:

10.3791/62672-v

DOI:
10.3791/62672-v

•

05:45 min
June 08, 2021

•

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1School of Chemistry and Materials Science,Nanjing Normal University, 2Institute for Cell Analysis,Shenzhen Bay Laboratory, 3Department of Chemistry,University of British Columbia

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Chaihu, L., Yao, X., Xu, X., Zhu, Z., Chen, D. D. Y., Wang, G. Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry. J. Vis. Exp. (172), e62672, doi:10.3791/62672 (2021).

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