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June 14, 2021
DOI:
1Department of Ophthalmology, Yong Loo Lin School of Medicine,National University of Singapore, 2Department of Ophthalmology,National University Hospital, Singapore, 3Institute of Molecular and Cell Biology (IMCB),Agency for Science, Technology and Research (A*STAR), 4Singapore Eye Research Institute (SERI), 5UCL Institute of Ophthalmology, 6Academic Clinical Program in Ophthalmology,Duke-NUS Medical School, 7Macula Center Saar, Eye Clinic Sulzbach,Knappschaft Hospital Saar, 8Department of Ophthalmology,University of Bonn
Summary
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O primata não humano (NHP) é um modelo ideal para estudar a terapêutica celular da retina humana devido às semelhanças anatômicas e genéticas. Este manuscrito descreve um método de transplante submacular de células epiteliais de pigmento retiniano no olho nHP e estratégias para prevenir complicações intraoperatórias associadas à manipulação macular.
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Seah, I., Liu, Z., Soo Lin Wong, D., Wong, W., Holder, G. E., Amutha Barathi, V., Lingam, G., Su, X., Stanzel, B. V. Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases. J. Vis. Exp. (172), e62638, doi:10.3791/62638 (2021).
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