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Horizontal Hippocampal Slices of the Mouse Brain
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Neuroscience
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JoVE Journal Neuroscience
Horizontal Hippocampal Slices of the Mouse Brain

Horizontal Hippocampal Slices of the Mouse Brain

English

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15,475 Views

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08:59 min

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September 22, 2020

DOI:

10.3791/61753-v

DOI:
10.3791/61753-v

•

08:59 min
September 22, 2020

•

85 Views
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1Laboratory of Endometrium, Endometriosis and Reproductive Medicine, Department of Development and Regeneration,KU Leuven, 2Laboratory of Ion Channel Research, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium and Department of Molecular Medicine,KU Leuven

Summary

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This article aims to describe a systematic protocol to obtain horizontal hippocampal brain slices in mice. The objective of this methodology is to preserve the integrity of hippocampal fiber pathways, such as the perforant path and the mossy fiber tract to assess dentate gyrus related neurological processes.

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Cite this Article

Van Hoeymissen, E., Philippaert, K., Vennekens, R., Vriens, J., Held, K. Horizontal Hippocampal Slices of the Mouse Brain. J. Vis. Exp. (163), e61753, doi:10.3791/61753 (2020).

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