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Begeleide machine learning voor semi-kwantificering van extracellulair DNA in Glomerulonephritis
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Immunology and Infection
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JoVE Journal Immunology and Infection
Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
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Begeleide machine learning voor semi-kwantificering van extracellulair DNA in Glomerulonephritis

Nederlands

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6,625 Views

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09:16 min

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June 18, 2020

DOI:

10.3791/61180-v

DOI:
10.3791/61180-v

•

09:16 min
June 18, 2020

•

15 Views
, , ,
1Department of Medicine,Monash University, 2Monash Micro Imaging,Monash University, 3Immunology Department,Monash Health

Summary

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Extracellulair DNA (ecDNA) dat vrijkomt bij de celdood is pro-inflammatorium en draagt bij aan ontsteking. Meting van ecDNA op de plaats van letsel kan de werkzaamheid van therapeutische behandeling in het doelorgaan bepalen. Dit protocol beschrijft het gebruik van een machine learning tool om de meting van ecDNA in nierweefsel te automatiseren.

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Cite this Article

O'Sullivan, K. M., Creed, S., Gan, P., Holdsworth, S. R. Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis. J. Vis. Exp. (160), e61180, doi:10.3791/61180 (2020).

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