Journal
/
Immunology and Infection
/
In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal Immunology and Infection
In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Please note that all translations are automatically generated. Click here for the English version.

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time

español

Automatically Generated

8,289 Views

•

09:19 min

•

May 24, 2020

DOI:

10.3791/61068-v

DOI:
10.3791/61068-v

•

09:19 min
May 24, 2020

•

9 Views
, , , , , ,
1Department of Pulmonary Diseases, Amsterdam UMC,VU University Medical Center, Amsterdam Cardiovascular Sciences (ACS), 2BIOS Lab-on-a-Chip group,University of Twente, 3Applied Stem Cell Technologies Group,University of Twente, 4Department of Cardio-thoracic Surgery, Amsterdam UMC,VU University Medical Center, 5Institute of Physiology,Charité-Universitätsmedizin, 6German Heart Center

Summary

Automatically generated

Presentamos un modelo de enfermedad vascular in vitro para investigar interacciones sanguíneas enteras con endotelio derivado del paciente. Este sistema permite el estudio de las propiedades trombogénicas de las células endoteliales primarias en diversas circunstancias. El método es especialmente adecuado para evaluar la trombogenicidad in situ y la terapia de anticoagulación durante diferentes fases de la coagulación.

Explore More Videos

In VitroMicrofluidicDisease ModelWhole BloodEndothelialBlood ClotThrombogenicityAnticoagulantInflammatoryPersonalized MedicinePulmonary ArteryFibroronectinEndothelial CellCD144Flow CytometryFlow ChamberGelatin

Read Article

Cite this Article

Manz, X. D., Albers, H. J., Symersky, P., Aman, J., van der Meer, A. D., Bogaard, H. J., Szulcek, R. In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time. J. Vis. Exp. (159), e61068, doi:10.3791/61068 (2020).

Download .ris file

Copy

Share Video

.

Copy