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Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
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JoVE Journal Chemistry
Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes

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7,602 Views

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05:34 min

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December 16, 2019

DOI:

10.3791/60767-v

DOI:
10.3791/60767-v

•

05:34 min
December 16, 2019

•

3 Views
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1Department of Organic Chemistry, Institute of Chemistry,University of Campinas

Summary

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A persulfate-promoted metal-free benzannulation of α,β-unsaturated compounds and alkynes in water toward the synthesis of unprecedented polyfunctionalized benzenes is reported.

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de Souza, G. F. P., Salles, A. G. Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes. J. Vis. Exp. (154), e60767, doi:10.3791/60767 (2019).

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