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Preparation of SNS Cobalt(II) Pincer Model Complexes of Liver Alcohol Dehydrogenase
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JoVE Journal Chemistry
Preparation of SNS Cobalt(II) Pincer Model Complexes of Liver Alcohol Dehydrogenase

Preparation of SNS Cobalt(II) Pincer Model Complexes of Liver Alcohol Dehydrogenase

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6,857 Views

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06:31 min

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March 19, 2020

DOI:

10.3791/60668-v

DOI:
10.3791/60668-v

•

06:31 min
March 19, 2020

•

2 Views
, , , , , , ,
1Department of Chemistry and Biochemistry,Fairfield University, 2Department of Chemistry,Keene State College

Summary

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The preparation of SNS pincer cobalt(II) model complexes of liver alcohol dehydrogenase is presented here. The complexes can be prepared by reacting the ligand precursor with CoCl2·6H2O and can then be recrystallized by allowing diethyl ether to slowly diffuse into an acetonitrile solution that contains the cobalt complex.

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Miecznikowski, J. R., Jasinski, J. P., Kaur, M., Bonitatibus, S. C., Almanza, E. M., Kharbouch, R. M., Zygmont, S. E., Landy, K. R. Preparation of SNS Cobalt(II) Pincer Model Complexes of Liver Alcohol Dehydrogenase. J. Vis. Exp. (157), e60668, doi:10.3791/60668 (2020).

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