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Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
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Chapters
- 00:00Title
- 00:52Preparation of Tarin Liposomal Nanocapsules
- 04:24Encapsulation Efficiency
- 05:58Size and Stability Determination
- 06:31Morphological Characterization
- 08:29Results
- 10:33Conclusion
This study describes classical hydration using the thin lipid film method for nanoliposome preparation followed by nanoparticle characterization. A 47 kDa-hydrophilic and globular protein, tarin, is successfully encapsulated as a strategy to improve stability, avoid fast clearance, and promote controlled release. The method can be adapted to hydrophobic molecules encapsulation.
