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Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

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06:52 min

October 30, 2018

DOI:

06:52 min
October 30, 2018

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Summary

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A modified Steglich esterification reaction was used to synthesize a small library of ester derivatives with primary and secondary alcohols. The methodology uses a non-halogenated and greener solvent, acetonitrile, and enables product isolation in high yields without the need for chromatographic purification.

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