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January 07, 2019
DOI:
1Department of Psychology, Hyperbaric Neuroscience Research Laboratory,University of South Florida, 2Department of Molecular Pharmacology and Physiology, Metabolic Medicine Research Laboratory, Morsani College of Medicine,University of South Florida, 3Institute for Human and Machine Cognition, 4Department of Pharmaceutical Sciences, College of Pharmacy,University of South Florida, 5James A. Haley VA Medical Center, 6Shriners Hospital for Children, 7Savaria Department of Biology,ELTE Eötvös Loránd University
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Aqui, apresentamos um protocolo para investigar as alterações do nível de ansiedade de modelos animais roedores. O elevado e mais labirinto teste (EPM), usado em conjunto com um vídeo, software de monitoramento, fornece um método confiável para documentar o efeito de diversos tratamentos potenciais do ansiolítico em cenários laboratoriais pré-clínicos.
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Ari, C., D’Agostino, D. P., Diamond, D. M., Kindy, M., Park, C., Kovács, Z. Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements. J. Vis. Exp. (143), e58396, doi:10.3791/58396 (2019).
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