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成体マウスにおける子宮頸部アデノ随伴ウイルス9（AAV9）ベクター送達
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Neuroscience
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JoVE Journal Neuroscience
Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice
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成体マウスにおける子宮頸部アデノ随伴ウイルス9（AAV9）ベクター送達

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16,921 Views

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08:32 min

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July 13, 2017

DOI:

10.3791/55770-v

DOI:
10.3791/55770-v

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08:32 min
July 13, 2017

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19 Views
, , , , , , , , , , , , ,
1Neuroregeneration Laboratory, Department of Anesthesiology,University of California, San Diego, 2Institute of Animal Physiology and Genetics,Czech Academy of Sciences, 3Department of Neurosurgery,University of California, San Diego, 4Institute of Neurobiology,Slovak Academy of Sciences

Summary

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本研究の目的は、成体マウスにおける新規な遺伝子サブ送達技術を用いて、脊髄アデノ随伴ウイルス9（AAV9）媒介遺伝子送達の効力および安全性を開発および検証することであった。

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Tadokoro, T., Miyanohara, A., Navarro, M., Kamizato, K., Juhas, S., Juhasova, J., Marsala, S., Platoshyn, O., Curtis, E., Gabel, B., Ciacci, J., Lukacova, N., Bimbova, K., Marsala, M. Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice. J. Vis. Exp. (125), e55770, doi:10.3791/55770 (2017).

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