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10:45 min
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May 31, 2017
DOI:
1Department of Bioengineering, School of Engineering and Applied Science,University of Pennsylvania, 2Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine,University of Pennsylvania, 3Center for Neurotrauma, Neurodegeneration & Restoration,Michael J. Crescenz Veterans Affairs Medical Center, 4School of Biomedical Engineering,Drexel University
Summary
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该手稿详细描述了微组织工程神经网络的制造：三维微米大小的构建体，包括跨越聚集的神经元群体的长比例的轴突区域，其包裹在管状水凝胶中。这些生活支架可以作为功能性继电器来重建或调节神经回路，或者作为模拟灰白色神经解剖学的生物学检验床。
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Struzyna, L. A., Adewole, D. O., Gordián-Vélez, W. J., Grovola, M. R., Burrell, J. C., Katiyar, K. S., Petrov, D., Harris, J. P., Cullen, D. K. Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling. J. Vis. Exp. (123), e55609, doi:10.3791/55609 (2017).
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