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aplicações de<em> In Vivo</em> Teste Funcional do Rato tibial anterior para a Avaliação da engenharia de tecidos Repair Músculo Esquelético
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair

aplicações de<em> In Vivo</em> Teste Funcional do Rato tibial anterior para a Avaliação da engenharia de tecidos Repair Músculo Esquelético

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13,360 Views

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07:13 min

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October 07, 2016

DOI:

10.3791/54487-v

DOI:
10.3791/54487-v

•

07:13 min
October 07, 2016

•

7 Views
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1Department of Pathology,University of Virginia, 2Department of Biomedical Engineering,University of Virginia, 3Department of Orthopaedic Surgery,University of Virginia

Summary

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We describe an in vivo protocol to measure dorsiflexion of the foot following stimulation of the peroneal nerve and contraction of the anterior crural compartment of the rat hindlimb. Such measurements are an indispensable translational tool for evaluating skeletal muscle pathology and tissue engineering approaches to muscle repair and regeneration.

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Cite this Article

Mintz, E. L., Passipieri, J. A., Lovell, D. Y., Christ, G. J. Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair. J. Vis. Exp. (116), e54487, doi:10.3791/54487 (2016).

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