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防御効力および肺免疫応答は、マウスに皮下および鼻腔内BCG投与後の
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Immunology and Infection
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JoVE Journal Immunology and Infection
Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
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防御効力および肺免疫応答は、マウスに皮下および鼻腔内BCG投与後の

日本語

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10,411 Views

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06:32 min

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September 19, 2016

DOI:

10.3791/54440-v

DOI:
10.3791/54440-v

•

06:32 min
September 19, 2016

•

3 Views
, , ,
1Department of Microbiology,University of Zaragoza

Summary

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We herein detail the methodology followed to compare protective efficacy and lung immune response induced by intranasal and subcutaneous immunization with BCG in mouse model. Our results show the benefits of pulmonary vaccination and suggest a role for IL17-mediated response in vaccine-induced protection.

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Uranga, S., Marinova, D., Martin, C., Aguilo, N. Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice. J. Vis. Exp. (115), e54440, doi:10.3791/54440 (2016).

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