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June 15, 2016
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This protocol describes basic procedural steps for performing whole-cell patch-clamp recordings. This technique allows the study of the electrical behavior of neurons, and when performed in brain slices, allows the assessment of various neuronal functions from neurons that are still integrated in relatively well preserved brain circuits.
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Segev, A., Garcia-Oscos, F., Kourrich, S. Whole-cell Patch-clamp Recordings in Brain Slices. J. Vis. Exp. (112), e54024, doi:10.3791/54024 (2016).
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