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April 14, 2016
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Human pain models are valuable tools used to assess the analgesic potential of novel compounds and predict their clinical efficacy, especially when used in an integrated manner. Although implementation of these models is complex, with proper execution, the pain models described in this protocol can provide predictive and reliable results.
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Hay, J. L., Okkerse, P., van Amerongen, G., Groeneveld, G. J. Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery. J. Vis. Exp. (110), e53800, doi:10.3791/53800 (2016).
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