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Studieren Mikrobielle Gemeinschaften<em> In-vivo-</em>: Ein Modell von Host-vermittelte Interaktion zwischen<em> Candida albicans</em> Und<em> Pseudomonas aeruginosa</em> In den Atemwegen
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Studieren Mikrobielle Gemeinschaften<em> In-vivo-</em>: Ein Modell von Host-vermittelte Interaktion zwischen<em> Candida albicans</em> Und<em> Pseudomonas aeruginosa</em> In den Atemwegen

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06:43 min

January 13, 2016

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06:43 min
January 13, 2016

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Summary

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While in vitro study of host-pathogen interactions allow the characterization of specific immune responses, in vivo models are required to observe the effects of complex responses. Using Candida albicans exposure followed by Pseudomonas aeruginosa-mediated lung infection, we established a murine model of microbial interactions involved in ventilator-associated pneumonia pathogenicity.

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