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In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model

In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model

DOI:

10.3791/52990-v

•

08:23 min

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April 12, 2016

•

Shorook Na’ara, Ziv Gil, Moran Amit

¹Otolaryngology, Head and Neck Surgery Department, The Laboratory for Applied Cancer Research, CRIR,Rambam Medical Healthcare Campus

Chapters

00:05Title
00:57Harvesting the Spinal Cord
02:51Isolating the Dorsal Root Ganglia (DRG)
04:43Culturing the DRG
06:20Results: Cancerous Neural Invasion of the DRG
07:34Conclusion

Summary

Automatic Translation

This video article shows the use of the dorsal root ganglia (DRG)/cancer cell model in pancreatic ductal adenocarcinoma.

Tags

Keywords: In Vitro Modeling Cancerous Neural Invasion Dorsal Root Ganglion Model Tumor Microenvironment Neural Niche Therapeutic Development Pharmacological Targeting Neural Remodeling Neural Invasion Euthanasia Dissection Spinal Cord Dorsal Root Ganglion

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