A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

Tatsuhiko Goto; Atsushi Toyoda

doi:10.3791/52973

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A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

JoVE Journal
Behavior

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JoVE Journal Behavior

A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

19,206 Views

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08:10 min

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November 24, 2015

DOI:

10.3791/52973-v

DOI:

10.3791/52973-v

•

08:10 min

November 24, 2015

•

18 Views

Tatsuhiko Goto^1,2, Atsushi Toyoda^1,2,3

¹College of Agriculture,Ibaraki University, ²Cooperation between Agriculture and Medical Science,Ibaraki University, ³United Graduate School of Agricultural Science,Tokyo University of Agriculture and Technology

Summary

Here, methods for developing a mouse model of subchronic and mild social defeat stress are described and used to investigate the pathogenic features of depression including hyperphagia- and polydipsia-like symptoms following increased body weight.

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Mouse Model Social Defeat Stress Depression Behavioral Deficits Physiological Deficits Body Weight Gain Food Intake Water Intake Social Behavior Atypical Depression Stress-induced Overeating Stress-induced Overdrinking Chronic Social Defeat Stress

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A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits

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