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Iridium (III) Lumineszierende Sonde zum Nachweis von Malaria-Protein Biomarker Histidin Rich Protein-II
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
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Iridium (III) Lumineszierende Sonde zum Nachweis von Malaria-Protein Biomarker Histidin Rich Protein-II

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8,991 Views

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12:52 min

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July 07, 2015

DOI:

10.3791/52856-v

DOI:
10.3791/52856-v

•

12:52 min
July 07, 2015

•

5 Views
, , , ,
1Department of Chemistry,Vanderbilt University

Summary

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Robust detection reagents are of increasing necessity for developing new malaria diagnostic tools. An iridium(III) probe was designed that emits long-lasting luminescent signal in the presence of a histidine-rich malarial protein biomarker. Detection of the protein either in solution or immobilized on a magnetic particle affords flexibility in application.

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Davis, K. M., Bitting, A. L., Markwalter, C. F., Bauer, W. S., Wright, D. W. Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II. J. Vis. Exp. (101), e52856, doi:10.3791/52856 (2015).

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