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PAW-拖动：一本小说，鼠标缸试验敏感性分析
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JoVE Journal Behavior
Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test
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PAW-拖动：一本小说，鼠标缸试验敏感性分析

DOI:
10.3791/52701-v

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09:14 min

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April 29, 2015

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,
1BioMedical Sciences, Faculty of Medicine,Memorial University of Newfoundland, 2Neurosciences, Faculty of Medicine,McGill University

Chapters

  • 00:00Title
  • 00:14Introduction
  • 03:07Set-up of the Mouse Cylinder Test
  • 04:32Conducting the Mouse Cylinder Test
  • 05:07Analysis of the Mouse Cylinder Test
  • 05:54Quantifying Paw Dragging Behavior
  • 06:59Identifying Behavior that is not a Paw Drag
  • 07:53Representative Results
  • 08:31Conclusion

Summary

Automatic Translation

Automatic Translation

气缸测试的经典前肢不对称分析常规地用于评估脑损伤或中风大鼠行为缺陷;但是，它无法检测一致赤字小鼠。这项研究表明，量化爪拖动行为是脑损伤的小鼠更敏感的分析。

Tags

Keywords: Paw-draggingMouse Cylinder TestFocal Ischemic DamageForelimb AsymmetryForelimb Motor CortexCortical Ischemic InjuryPhotothrombosisEndothelin-1Functional RecoveryTransgenic Mouse Strains

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