This manuscript describes a protocol to examine the olfactory system of rodents. The olfactory habituation/dishabituation test will allow investigators to determine whether a mouse habituates to a repeatedly presented odor and whether the mouse demonstrates dishabituation when presented a novel odor.
Arbuckle, E. P., Smith, G. D., Gomez, M. C., Lugo, J. N. Testing for Odor Discrimination and Habituation in Mice. J. Vis. Exp. (99), e52615, doi:10.3791/52615 (2015).